ABSTRACT
Background: A significant reason of maternal deaths is postpartum hemorrhage (PPH) that accounted for one-quarter of all maternal mortality globally. Primary postpartum hemorrhage (PPH) is conventionally described as a loss of blood of ≥ 500 ml within the first 24 hours following childbirth.
AIM OF THE WORK using carbetocin versus misoprostol in postpartum hemorrhage prevention in sufferers with intense preeclampsia.
Patients and Methods: A randomized prospective study is done to compare use carbetocin vs misoprostol in postpartum hemorrhage prevention with severe preeclampsia. In the present research a total of 100 patients who attended Sohag general Hospital included. First group was formed of 50 pregnant women candidate for cesarean section delivery with intense preeclampsia obtained carbetocin (IV injection (100 ug ,one ampoule pabal) following baby delivery. While the second group is formed of another 50 pregnant women that are also candidate for cesarean section delivery with intense preeclampsia but obtained Sublingual 600 ug misoprostol following baby delivery.
Results: The findings revealed that there was a highly substantial statistical variation among the baseline & post-partum Hb & HCT in both Misoprostol group and carbitocin group.
Conclusion: Carbetocin is more effective than Misoprostol in preventing incidence of atonic postpartum hemorrhage in patients performing elective caesarean delivery with severe preeclampsia.
Keywords: Postpartum Haemorrhage; Preeclampsi; Carbetocin; Misoprostol