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134490

Risk of hypocalcemia after total thyroidectomy and bilateral central neck dissection in patients with well differentiated thyroid carcinoma.

Article

Last updated: 22 Jan 2023

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Abstract

Background: Hypocalcaemia is a grave complication after thyroid surgery with signs ranging from paresthesia up to laryngospasm. Avoiding this complication is mandatory to avoid lifelong calcium and vitamin D supplements.
Aim of the work: to assess the risk of hypocalcaemia after thyroid surgery and the factors contributing to it.
Patients and methods: this study was conducted on 50 patients with well differentiated thyroid carcinoma admitted to Sayed Galal hospital and they were divided into 3 groups: A, B and C.
Results: Group B patients had transient hypocalcaemia and PTH levels were in normal range, thus suffering from parathyroid dysfunction. Calcium levels returned to normal range after a mean of 15.5 days.
Group C patients remained hypocalcemic for over six months and PTH levels were below normal range thus defining absolute hypoparathyroidism.
In terms of age, gender, tumor size and stage, group C patients were older, had no female prevalence, had slightly larger tumors and presented at late stages. Preoperative calcium levels were not a risk factor as group C patients had the highest mean of ionized calcium and group B patients had lower mean of total calcium level than those of group C.
Conclusion: The most important risk factor for post-thyroidectomy hypocalcaemia is the surgical technique. Meticulous dissection to preserve the blood supply to the parathyroid glands and careful handling of the parathyroid tissue are equally important to preserving the parathyroids themselves. Other risk factors include older age, large tumors and late stages.

DOI

10.21608/aimj.2021.44026.1327

Keywords

hypocalcaemia, Thyroid carcinoma, Total Thyroidectomy, central neck dissection, Hypoparathyroidism

Authors

First Name

Muhammad

Last Name

Gohar

MiddleName

Gaber

Affiliation

Department of surgery, Damanhur oncology center, Elbeheira, Egypt

Email

mgohar0712@gmail.com

City

Damanhur

Orcid

-

First Name

Ahmed

Last Name

Mohamed

MiddleName

El-Sayed

Affiliation

Department of oncosurgery, Al Azhar University, Cairo, Egypt

Email

dr.ahmed.elsayed.surg2020@gmail.com

City

Cairo

Orcid

-

First Name

Hamed

Last Name

Al-Azzouny

MiddleName

Ahmed

Affiliation

Department of oncosurgery, Al Azhar University, Cairo, Egypt

Email

prof.hamed.azzouny@gmail.com

City

-

Orcid

-

Volume

1

Article Issue

11

Related Issue

19841

Issue Date

2020-11-01

Receive Date

2020-10-01

Publish Date

2020-11-01

Page Start

139

Page End

143

Print ISSN

2682-3381

Online ISSN

2682-339X

Link

https://aimj.journals.ekb.eg/article_134490.html

Detail API

https://aimj.journals.ekb.eg/service?article_code=134490

Order

6

Type

Original Article

Type Code

710

Publication Type

Journal

Publication Title

Al-Azhar International Medical Journal

Publication Link

https://aimj.journals.ekb.eg/

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Details

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Article

Created At

22 Jan 2023