Background: Posterior Pedicle screw fixation has step by step become popular to thoracolumbar fracture management. Since Roy-Camille et al used application of plates with pedicle screws for thoracolumbar fractures in 1963. Aim of the work: to evaluate the percutaneous transpedicular fixation for management of lumbar fractures. Patients and Methods: This research was done on 20 patients presented by lumbar spine fractures; they were treated with percutaneous transpedicular fixation and stabilization at Al-Azhar University hospitals from June 2019 to February 2020. All patients were without neurological deficits they were fixed either one level above and one level below or two levels above and two levels below the fractured vertebra. Results: Clinical and functional outcomes are preferable or comparable to conventional open procedures. The key disadvantages of this procedure are the steep learning curve and radiation exposure to both doctors, nurses and surly patients, which may be reduced as much as possible by using the new 3D CT screw insertion process. Conclusion: Percutaneous transpedicular spine fixation is a secure technique that follows the same principles as open procedures, allowing the surgeon to conduct biomechanically strong internal spinal fixation with minimal tissue damage, and is a suitable choice for the treatment of unstable thoracolimber fractures with no neurological deficit. This has the benefit of short-time surgery, no loss of blood, almost no muscle damage results in less postoperative pain than conventional open procedures, short hospitalization, early mobilization, a quicker return to work and a low risk of complications