Background: To detect the effectiveness of OCT-A in evaluation of foveal avascular zone (FAZ) alterations in eyes with retinal vein occlusion .
Objectives: To investigate the relationship between best-corrected visual acuity (BCVA) and the FAZ in patients with (RVO) evaluated with (OCT-A) in comparison to the unaffected fellow eyes.
Patients and Methods: We retrospectively reviewed the medical records of 15 patients with (RVO); BRVO in 8 patients, CRVO in 7 patients) and we considered the unaffected fellow eyes of these patients as a control group, who were evaluated by OCT-A by a 6 mm × 6-mm region scan centered on the fovea and parafoveal area. The (FAZ), and foveal and parafoveal vascular density in superficial and deep vascular plexuses were analyzed.
Result: The mean superficial FAZ area (SL FAZ area) measured 0.40mm in the study group and 0.30mm in the control group. The mean deep FAZ area(DL FAZ area) measured 0.46 mm in the study group and 0.35 mm in the control group. The SL FAZ and DL FAZ areas in eyes with RVO were larger than those in control eyes (P = 0.002, P = 0.033).We found a negative correlation between the BCVA and the superficial FAZ area in eyes with RVO (r = _0.42, P = 0.11).We found a negative correlation between the BCVA and deep FAZ area in the control group(r=_0.30, P 0.26).
Conclusions: OCT-A allows detecting FAZ enlargement.Also, we found statistically significant negative correlation between FAZ enlargement and BCVA in patients with RVO.