Abstract:
To date, coffee drinks lies as the second largest trade widely consumed in a major variety of formats attributed to its easy preparation and desirable taste. There were growing concerns detected the correlation between coffee beverage consumption and variant clinical manifestations on the drinkers. The based study was designed to elucidate the potential aggravating influences derived from instant coffee drinks. Forty adult male albino rats within average age 3 months and body weight 120-150 gm divided into 4 groups. Group (1); used as control. While, group 2, 3 & 4 orally administrated coffee of Mocha (Cappucinno) type at 0.726, 1.44 and 2.16 ml, respectively daily for 7 weeks. After the experiment time out, blood samples were withdrawn for evaluation of kidney function tests and lipid profiles. In Addition, kidney and heart tissues collected for histopathology. From a biochemical point of view, Cappucinno was resulted in a significant increase in urea, creatinine and uric acid besides significant elevation in blood glucose, cholesterol and triglycerides levels when compared with control. Histopathologically, necrosis with inflammation of the renal tubules and myocardium were detected, in addition to congestion with dilatation of the blood vessels. It could be concluded that consumption of Cappuccino as instant coffee drinks conducted deleterious effect on the drinkers.