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191878

Relationship between C-Reactive Protein / Albumin Ratio and Coronary Artery Disease Severity in Patients with Chronic Coronary Syndromes

Article

Last updated: 22 Jan 2023

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Abstract

Background: Syntax score (SS), which is an angiographic technique used in categorizing the severity of coronary artery disease (CAD), has a significant prognosis in coronary artery disease (CAD) and explain an important information concerning selection of revascularization policy. C-reactive protein (CRP) and albumin are markers of inflammation, and high levels of them are associated with high SS.
Aim of the Work: To detect whether baseline CRP to albumin ratio (CAR), an easily available and novel inflammatory indicator, is associated with SS in patients with chronic coronary syndromes.
Methodology: This study was carried out on 100 patients having chronic coronary syndromes for whom, a diagnostic coronary angiography was done at Sohag University Cath. Lab unit in the period from January -July 2021. Patients were divided randomly into two equal groups:
*Group I, patients having low SS (≤22).
*Group II, patients having intermediate-high SS (>22).
Results: C-Reactive Protein/Albumin Ratio was significantly higher in patients having intermediate-high SS group (P < .0001). In multivariate regression analysis, CAR was an independent indicator of intermediate-high SS group together with LDL.
Conclusion: CAR was more intensely related to the severity of CAD than CRP and albumin alone and was detected to be an independent indicator for intermediate- high SS group.

DOI

10.21608/niles.2021.88465.1056

Keywords

albumin, coronary artery disease severity, C-reactive protein, C-reactive protein/albumin ratio, Chronic coronary syndromes

Authors

First Name

Alaa

Last Name

Ghaleb

MiddleName

Ahmed

Affiliation

Internal Medicine Sohag university

Email

alaaghalib10@yahoo.com

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Orcid

-

First Name

Ahmed

Last Name

Boghdady

MiddleName

-

Affiliation

Sohag Faculty of Medicine, Internal Medicine Department

Email

ahbomed@yahoo.com

City

-

Orcid

-

First Name

Mohammed

Last Name

Shehab

MiddleName

-

Affiliation

Sohag Faculty of Medicine, Internal Medicine Department

Email

mshehab404@yahoo.com

City

-

Orcid

-

First Name

Usama Mohammed

Last Name

Abd Elaal

MiddleName

-

Affiliation

Sohag Faculty of Medicine, Internal Medicine Department

Email

osamelaal74@yahoo.com

City

-

Orcid

-

Volume

4

Article Issue

Geriatric Medicine

Related Issue

22097

Issue Date

2021-09-01

Receive Date

2021-07-31

Publish Date

2021-09-01

Page Start

49

Page End

57

Print ISSN

2636-3224

Online ISSN

2636-3232

Link

https://niles.journals.ekb.eg/article_191878.html

Detail API

https://niles.journals.ekb.eg/service?article_code=191878

Order

4

Type

Original Article

Type Code

695

Publication Type

Journal

Publication Title

NILES journal for Geriatric and Gerontology

Publication Link

https://niles.journals.ekb.eg/

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Article

Created At

22 Jan 2023