Background:
Elevated intraocular pressure (IOP) is one of the most important factors for diagnosis and monitoring of glaucoma. IOP is currently the only modifiable risk factor for glaucoma, cornea is the transparent tissue covering the front of the eye. It is a powerful refracting surface, providing 2/3 of the eye's focusing power. The adult cornea is only about 1/2 millimeter thick and is comprised of 6 layers: epithelium, Bowman's membrane, stroma, Dua's layer, Descemet's membrance and endothelium.

Objectives:
correlation of Corneal Biomechanics (ORA) with perimetry, IOP and OCT optic nerve results in eyes with primary open angle glaucoma and glaucoma suspect patients.

Patients and Methods:
This study is a prospective cross-sectional study, ocular response analyzer (ORA) parameters were measured in 40 patients with correlation to their Intraocular pressure (IOP), Perimetry and ocular coherence tomography (OCT) retinal nerve fiber layer thickness (RNFL) on 80 eyes, Patients ages range between 45-65 years old. The study was prepared on patients seeking treatment in ophthalmology polyclinic in The Memorial Institute of Ophthalmic Researches in Giza , they were screened to identify those with primary open angle glaucoma and glaucoma suspect patients.

Results:
Our study revealed that the corneal biomechanics Parameters are significantly lower in patients with advanced primary open angle glaucoma (POAG).

Conclusion:
Studying corneal biomechanics is essential for early diagnosis of glaucoma suspect and follow up of primary open angle glaucoma patients.