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87848

A Comparative Study Between Transplantation of Conjunctival Limbal Autograft with Mitomycin C and Amniotic Membrane Transplantation with Mitomycin C in Recurrent Pterygium

Article

Last updated: 22 Jan 2023

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Abstract

Introduction :
Pterygium, a wing‐shaped encroachment of the cornea by the conjunctiva, Conjunctival limbal autograft with stem cell (CLAU) or amniotic membrane transplantation (AMT) has been widely adopted in the management of pterygium.

Purpose:
To compare the efficacy and the complications of conjunctival limbal autograft (CLAU) with mitomycin C 0.2 % and amniotic membrane transplantation (AMT) with mitomycin C 0.2 % for treatment of recurrent pterygium
Subject and methods:
80 eyes of 60 patients clinically diagnosed with recurrent pterygium were divided into two groups , group A included 40 eyes underwent pterygium excision and MMC 0.2% with CLAU , group B included 40 eyes underwent pterygium excision and MMC 0.2% with AMT . Recurrence was defined as fibrovascular tissue extension of more than one mm onto the cornea in the area of previously excised pterygium. Mean follow up period 8±1 month . Recurrence was compared in each group by using ӽ2 test
Results:
No major postoperative complications occurred during 6-9 months of follow-up . In CLAU group (A)only 5 eyes of recurrence occur(12.5%)after 7 months of follow up . Recurrence occur in 12 eyes (30%)in AMT group (B) after 6 months ( P value =0.043, ӽ2 test).The operated site was look like the normal adjacent site in 77%of the non recurrence group A versus 10% in group B

Conclusion:
CLAU with MMC is more effective than AMT with MMC for treatment of recurrent pterygium and the final cosmetic appearance is more acceptable in CLAU group than AMT group B .

DOI

10.21608/niles.2020.27388.1011

Keywords

Recurrent, Pterygium, AMT, limbal graft

Authors

First Name

mohammed

Last Name

AbdElKhalek

MiddleName

-

Affiliation

Ophthalmology Department, Faculty of Medicine, Beni-Suef University, Egypt

Email

nabi_mar@yahoo.com

City

cairo

Orcid

-

First Name

Waleed

Last Name

Mahran

MiddleName

M

Affiliation

Ophthalmology Department, Faculty of Medicine, Beni-Suef University, Egypt

Email

-

City

-

Orcid

-

First Name

Safaa

Last Name

Aboud

MiddleName

A

Affiliation

Ophthalmology Department, Faculty of Medicine, Beni-Suef University, Egypt

Email

-

City

-

Orcid

-

Volume

3

Article Issue

Geriatric ophthalmology

Related Issue

8595

Issue Date

2020-05-01

Receive Date

2020-04-06

Publish Date

2020-05-01

Page Start

1

Page End

7

Print ISSN

2636-3224

Online ISSN

2636-3232

Link

https://niles.journals.ekb.eg/article_87848.html

Detail API

https://niles.journals.ekb.eg/service?article_code=87848

Order

1

Type

Original Article

Type Code

695

Publication Type

Journal

Publication Title

NILES journal for Geriatric and Gerontology

Publication Link

https://niles.journals.ekb.eg/

MainTitle

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Details

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Article

Created At

22 Jan 2023