To investigate the effect of foilar application of salicylic rates and yeast extracton yield and quality of wheat, in this respect the two experiments were carried out at the Experimental Farm, Faculty of Agriculture, Saba Basha, Alexandria University, Alexandria Governorate, Egypt, during the two winter seasons of 2019/2020 and 2020/2021. This factorial experiment was laid out in randomized complete block design (RCBD) with three replications in both seasons. The first factor was salicylic acid concentrations (spray water, 150, 300 and 450 ml/l), while the second factor was yeast (water = control, 2, 4 and 6 g/l water) was in both seasons. The obtained results showed that foliar application of salicylic acid (SA) and yeast extract of wheat significantly affected yield and its component, whereas increasing of SA and yeast extract increased yield and yield component characters of wheat in both seasons. The interaction between SA and yeast was significant on all the studied characters, where planting Giza 171 with foliar application of 450 ppm SA/L and 4 and 6 g yeast/L recorded the highest ones in the two seasons under the study conditions.