The present study was carried out at Abess, Alexandria, Egypt, during the two seasons of 2018/2019 and 2019/2020 to study the effect of water stress and foilar application of salicylic rates on yield and quality of wheat. This experiment was laid out in a split plot system with three replications in both seasons. The main plots were water stress treatments (normal irrigation, skipping the first irrigation at the age of 50 days, skipping the second irrigation at the age of 70 days, and skipping the third irrigation at the age of 90 days from sowing), while salicylic acid (SA) concentration (water = control, 1 mM;  2 mM and 3 mM) distributed in a sub plot in both seasons. The obtained results showed that sowing wheat cultivar namely Shandaweel- 1 with foliar application of salicylic acid (SA) twice at 50 and 70 days after sowing (DAS) at the rate of 2 mM/l under normal irrigation or skipping one irrigation at the first or the second irrigation achieved the highest mean value of yield, yield components and protein (%) in grain under study conditions at Abess, Alexandria Governorate, Egypt.