The present study was carried out at Nubaria, El-Beheira Governorate, Egypt, during the two summer seasons of 2018 and 2019 to study the effect of foilar application of salicylic rates on yield and quality of some soybean varieties under drip irrigation. This experiment was laid out in a split-plot system with three replications in both seasons. The main plots were soybean varieties (Giza111, Giza 22, J350, and J356), while subplot allocated by the number of spray times of salicylic acid (SA) concentration (water = control, once after 30 DAS, twice after 30, and 50 DAS, and three times after 30, 50 and 70 days after sowing=DAS) was in both seasons. The obtained results showed that foliar application of salicylic acid (SA) of the four soybean varieties significantly affected plant height (cm), number of branches/plant, number of pods/plant, 100- seed weight (g), seed yield (kg/fed), straw yield (kg/fed), biological yield (kg/fed), as well as oil content (%), whereas Giza 111 recorded the highest values of the all the study, also increasing of times of foliar application of SA increased the pervious characters comparing with the control treatments (water spray) in both seasons. The interaction between varieties and number of spray times of SA was significant on all the studied characters, where planting Giza 111 with twice foliar application of SA at the rate 1000 ppm recorded the highest ones in the two cropping seasons in drip water irrigation under the study conditions.