The present study was carried out at Nubaria Region, El- Beheira Governorate, Egypt, during the two summer seasons of 2019 and 2020 to study the effect of foilar application of salicylic (SA) and ascorbic acids (ASA) on yield and quality of soybean cv. Giza 111 under drip irrigation. This experiment was laid out in the factorial experiment (two factors) in randomized complete blocks design (RCBD) in three replications. The first factor was salicylic acid (SA) concentrations (water = control, 500, 1000, and 1500 ppm), while the second factor was ascorbic acid (ASA) concentration (water = control, 500, 1000 and 1500 ppm) in both seasons. The obtained results showed that foliar application of salicylic acid (SA) and ascorbic acid (ASA) significantly affected plant height (cm), number of branches/plant, number of pods/plant, 100- seed weight (g , seed yield (kg/fed), straw yield (kg/fed), biological yield (kg/fed), harvest index (%), and oil content (%) in the two seasons, whereas increasing of SA and ASA from 500 up to 1500 ppm increased all the studied characters as compared with the control treatments (water spray) in both seasons. The interaction between the foliar application of SA and ASA concentration was significant on all the studied characters in both seasons, where using 1500 or 1000 ppm SA/fed + 500 or 1000 ppm ASA achieved the highest mean values of all the studied characters in the two cropping seasons in drip water irrigation under the study conditions.