In this study, we investigated the in-vitro effect of 11 medicinal plants' methanolic extracts against 3 strains of multidrug resistance E coli which were confirmed via the VIETK2 system and were given numbers (1, 2, 3) to distinguish each one.
            Strain 1and 3 showed complete resistance to 8 different types of antibiotics, while strain 2 showed 11 types of antibiotics out of 11 types of antibiotics that were used in this study.
            Strain 1 showed sensitivity towards extracts of (Green tea, Fennel seed, Pomegranate peel), strain 2 showed sensitivity towards (Fennel seed, Sage leaves, Thyme leaves) extracts, and strain 3 showed sensitivity towards (Green tea, Fennel seed, Pomegranate peel, Sage leaves, Thyme leaves).