Extracts of pomegranate peel and apricot kernel were evaluated against bacteria, fungi and insect. Pomegranate extract appear potency when used against bacteria (Escherichia coli, Pseudomonas aeruginosa, Morganella sp, Micrococcus sp, Staphylococcus aureus), fungi (Fusarium sp., Alternaria alternata, Penicillium sp. And Aspergillus niger) and yeast (Candida albicans), but apricot was effective only on three types of fungi (Fusarium sp, A. alternata and A. niger) but not effective against any type of bacteria and yeast (Candida albicans) at concentrations which used in this study. Evaluation of pomegranate and apricot extracts appear different degree of potency against Culex pipiens larvae, apricot extract more effective than pomegranate extract. The potency was increased when make binary mixture of both extracts. Apricot extract appear also effect on life cycle of mosquitoes by decrease pupation percent and adult emergence percent comparing with control.