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16496

Is Herpes Simplex Virus (HSV) infection a risk factor for nasopharyngeal carcinoma?

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Last updated: 03 Jan 2025

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Abstract

Objective: The aim of this study was to screen for the presence
of HSV in patients with nasopharyngeal Carcinoma (NPC). Methodology:
Formalin fixed paraffin wax processed NPC tissue were obtained from 150 tissue
blocks and retrospectively investigated for the presence of HSV-1 and HSV-2
using polymerase Chain Reaction (PCR). Results: Of the 150 NPC tissue
specimens, Herpes Simplex Virus type 2 (HSV-2) was identified in 18/150 (12%)
samples. Out of the 18 samples infected with HSV-2, 15/97 (15.5%) among males
and 3/53(5.7%) were among females. Conclusion: The present have shown
some weak links between HSV and NPC. The great majority of samples harboring
HSV were also found to harbor EBV, which suggests the potentiality of EBV over
HSV.

DOI

10.21608/eajbsg.2014.16496

Keywords

Herpes Simples Virus, Nasopharyngeal carcinoma

Authors

First Name

Hussain

Last Name

Ahmed

MiddleName

Gadel karim

Affiliation

Department of Pathology, College of Medicine, Molecular Diagnostics and Personalized Therapeutics Unit, University of Hail, KSA; Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan

Email

hussaingad1972@yahoo.com

City

-

Orcid

-

First Name

Rania

Last Name

Suliman

MiddleName

Saad Abdul Gader

Affiliation

Department of Histopathology and Cytology, Faculty of Medical Laboratory Science, Sudan University for Science and Technology, Sudan

Email

-

City

-

Orcid

-

First Name

Mohammed

Last Name

Abd El Aziz

MiddleName

Siddig

Affiliation

Department of Histopathology and Cytology, Faculty of Medical Laboratory Science, Sudan University for Science and Technology, Sudan

Email

-

City

-

Orcid

-

First Name

Fawaz

Last Name

Alshammary

MiddleName

D.

Affiliation

Department of Medical Laboratory Science, College of Applied Medical Science, University of Hail, KSA

Email

-

City

-

Orcid

-

First Name

Faris

Last Name

Altom

MiddleName

Margani

Affiliation

Department of Medical Laboratory Science, College of Applied Medical Science, University of Taibah, KSA

Email

-

City

-

Orcid

-

First Name

Ibrahim

Last Name

Ginawi

MiddleName

A

Affiliation

Department of Pathology, College of Medicine, Molecular Diagnostics and Personalized Therapeutics Unit, University of Hail, KSA; Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan

Email

-

City

-

Orcid

-

Volume

6

Article Issue

2

Related Issue

3522

Issue Date

2014-12-01

Receive Date

2018-10-13

Publish Date

2014-12-01

Page Start

27

Page End

32

Print ISSN

2090-0872

Online ISSN

2090-0880

Article File

EAJBSG_Volume 6_Issue 2_Pages 27-32.pdf

PDF . 287.3kB

Link

https://eajbsg.journals.ekb.eg/article_16496.html

Detail API

https://eajbsg.journals.ekb.eg/service?article_code=16496

Order

4

Type

Original Article

Type Code

689

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, G. Microbiology

Publication Link

https://eajbsg.journals.ekb.eg/

MainTitle

Is Herpes Simplex Virus (HSV) infection a risk factor for nasopharyngeal carcinoma?

Details

Type

Article

Created At

22 Jan 2023