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16487

The Antibacterial Activity Of Bee Venom On Selected Pathogenic Bacteria

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Last updated: 03 Jan 2025

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Abstract

Honey
bee venom of Apis mellifera carnica with LD50 equal to
290µg/mouse, was analyzed by HPLC (high performance liquid chromatography) to
perform its activity and found that it contains the most important active
compounds which are Melittin (52.1%), Phospholipase A2(11.9%), and Apamin (2.3%)
then tested against selected pathogenic bacteria invitro. The selected
bacteria were Methicillin resistant Staphylococcus aureus (MRSA), Proteus
sp., E.coli ,Salmonella sp., The results showed that bee venom has high
significant effect on Gram positive bacteria (MRSA), and from moderate to low
significance on gram negative bacteria (Proteus sp., E.coli ,
Salmonella sp.) therefore Bee venom could be a promising alternative
antibiotic

DOI

10.21608/eajbsg.2015.16487

Keywords

Bee venom, Pathogenic bacteria, HPLC, MRSA, Antibacterial activity

Authors

First Name

Amany

Last Name

Salem

MiddleName

Z.

Affiliation

Entomology Department, Faculty of Science, Ain Shams University

Email

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City

-

Orcid

-

First Name

El-Sayed

Last Name

Bedair

MiddleName

H.

Affiliation

Beekeeping, Agriculture Research Center, Giza

Email

-

City

-

Orcid

-

First Name

Wael

Last Name

Hablas

MiddleName

R.

Affiliation

Clinical pathology Department, Faculty of medicine Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Abir

Last Name

Elfiky

MiddleName

A.

Affiliation

Director of ANDI center of excellence in antivenom research, Vacsera, Egypt

Email

-

City

-

Orcid

-

First Name

Basma

Last Name

Hussein

MiddleName

I.

Affiliation

Faculty of science Ain shams university

Email

-

City

-

Orcid

-

Volume

7

Article Issue

1

Related Issue

3520

Issue Date

2015-12-01

Receive Date

2018-10-13

Publish Date

2015-12-01

Page Start

69

Page End

75

Print ISSN

2090-0872

Online ISSN

2090-0880

Article File

EAJBSG_Volume 7_Issue 1_Pages 69-75.pdf

PDF . 429.4kB

Link

https://eajbsg.journals.ekb.eg/article_16487.html

Detail API

https://eajbsg.journals.ekb.eg/service?article_code=16487

Order

8

Type

Original Article

Type Code

689

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, G. Microbiology

Publication Link

https://eajbsg.journals.ekb.eg/

MainTitle

The Antibacterial Activity Of Bee Venom On Selected Pathogenic Bacteria

Details

Type

Article

Created At

22 Jan 2023