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242059

Prevalence of Opportunistic Parasites Among Liver Cirrhosis Patients in Beni-Suef

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Last updated: 22 Jan 2023

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Abstract

Liver cirrhosis patients are susceptible to many opportunistic parasitic infections such as Cryptosporidium spp., Isospora belli (I. belli) and Blastocystis hominis (B. hominis)as there are variable degrees of immune alteration accompanying cirrhosis, that affect the innate and adaptive immunity, according to the extent of liver damage.
             A total of 135 stool samples were collected from patients who attended the outpatient clinics of Tropical Medicine Departments, Faculty of Medicine, and Beni-Suef University Hospitals. Patients were classified into two groups: the cases group which contained 90 patients suffering from liver cirrhosis with gastrointestinal (GIT) symptoms (mainly abdominal pain and diarrhea) and the control group formed of 45 patients complaining of gastrointestinal symptoms without liver cirrhosis. The samples were microscopically examined directly by wet saline and Lugol's iodine mounts. Negative specimens were reexamined after the formal-ether concentration method. Samples were then stained with modified Ziehl-Neelsen (MZN) stain for the suspected presence of Cryptosporidium spp.
               The most prevalent protozoan was B. hominis in both cases and control groups, followed by Cryptosporidium spp. with a higher percentage in the cases group(26.7% vs 11.1% and 21.1% vs 4.4% respectively), and both were statistically significant (P=0.038 and 0.012 respectively).  Capillaria was the most frequent helminth found in both cases and control groups (6.7% vs 4.4%). However, the correlation to liver cirrhosis was insignificant (p < /em>= 0.718).

DOI

10.21608/eajbse.2022.242059

Keywords

Liver cirrhosis, Immunocompromised patients, Opportunistic parasites, B. hominis, Cryptosporidium spp

Authors

First Name

Shimaa

Last Name

Ibrahim

MiddleName

S.

Affiliation

Department of Medical Parasitology, Faculty of Medicine, Beni-Suef University.

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City

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Orcid

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First Name

Naglaa

Last Name

Imam

MiddleName

F.A.

Affiliation

Department of Medical Parasitology, Faculty of Medicine, Cairo University.

Email

naglaa-fouad@cu.edu.eg

City

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Orcid

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First Name

Mousa

Last Name

Ismail

MiddleName

A.M.

Affiliation

Department of Medical Parasitology, Faculty of Medicine, Cairo University.

Email

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City

-

Orcid

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First Name

Asmaa

Last Name

Sieddek

MiddleName

S.

Affiliation

Department of Gastroenterology, Hepatology and Tropical Medicine, Beni-Suef University.

Email

-

City

-

Orcid

-

First Name

Amira

Last Name

Raafat

MiddleName

-

Affiliation

Department of Medical Parasitology, Faculty of Medicine, Cairo University.

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City

-

Orcid

-

Volume

14

Article Issue

1

Related Issue

31171

Issue Date

2022-06-01

Receive Date

2022-04-08

Publish Date

2022-06-05

Page Start

133

Page End

142

Print ISSN

2090-0783

Online ISSN

2090-0856

Link

https://eajbse.journals.ekb.eg/article_242059.html

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https://eajbse.journals.ekb.eg/service?article_code=242059

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12

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Original Article

Type Code

687

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, E. Medical Entomology & Parasitology

Publication Link

https://eajbse.journals.ekb.eg/

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Article

Created At

22 Jan 2023