Mosquitoes can spread a variety of infections that can cause serious health problems and even death, including malaria, filariasis, yellow fever, and a variety of other diseases. Mosquito control using insecticides is presently the most extensively utilized disease control strategy. Insecticide resistance has emerged, and pesticides have detrimental consequences for the environment, non-target species, and human health. To avoid these issues, bio-control strategies for mosquito vectors have been developed. Bio-control is a pest-reduction method that is both environmentally friendly and effective. This article provides an overview of the most effective biological mosquito control methods, including predators (larvivorous fish and toxorhynchites larva), entomopathogenic fungi, bacteria, viruses, nematodes, herbal mosquito control, the Sterile Insect Technique, and genetically modified mosquitos. In this paper, we will review the existing research on biocontrol agents for mosquito vectors and emphasize the relevance of biological control. Finally, we'll go over the benefits and drawbacks of biological control measures.