Schistosoma mansoni is one of the parasites causing schistosomiasis, a disease that threatens millions of people worldwide. The treatment of schistosomiasis is a critical point in research and includes fighting either adult worms or any of the different life cycle stages. Sodium hypochlorite (NaOCl) is the main constituent of the bleaching solution, in the present study different concentrations of the bleaching solution were used to recognise their effects on the surface topography of Schistosoma mansoni eggs; 1, 5, 10 and 30 ppm of were used at time scale of 15, 30 and 60 minutes for each separate treatment. All of the concentrations experimented in this study affected the eggs if compared to the control ones.  The surface topography of the eggs was greatly changed with increasing concentration and time, since, at higher concentration of the bleaching solution, some eggs were shrunk, deformed and egg shells were cracked. So, the bleaching solution may therefore be a useful treatment for Schistosomiasis mansoni.