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14457

Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?

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Last updated: 03 Jan 2025

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Abstract

Ultrastructural evidence from Phlebotomus
langeroni experim-entally infected with Leishmania infantum
was found from day 4 postinfection to support the hypothesis that shed midgut
cells act as an important nutrient source for the parasite. Thirteen areas of
degenerating cells occurred in 12 sections of infected flies compared to none
in complementary controls 8 days post-infection. Parasites penetrated
degenerating cells in 7 of 30 flies sectioned (days 8-11 post-infection), and
were frequently found packed around shed cells in the gut lumen. No
melanisation was observed, suggesting that although higher cell turnover was
probably induced by parasites they did not destroy intact cells.

DOI

10.21608/eajbse.2018.14457

Keywords

sand flies, Phlebotomus langeroni, Leishmania infantum, experimental infection, Ultrastructure

Authors

First Name

Sanaa

Last Name

El - Sattar

MiddleName

A.

Affiliation

Research & Training Center on Vectors of Diseases, Ain Shams University, Cairo, Egypt

Email

badersanaa@yahoo.com

City

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Orcid

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First Name

Rod

Last Name

Dillon

MiddleName

J.

Affiliation

Imperial College, London, UK.

Email

-

City

-

Orcid

-

First Name

Bahira

Last Name

El - Sawaf

MiddleName

M.

Affiliation

Faculty of Science, Ain Shams University, Cairo, Egypt

Email

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City

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Orcid

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Volume

10

Article Issue

1

Related Issue

2848

Issue Date

2018-06-01

Receive Date

2018-09-24

Publish Date

2018-06-01

Page Start

21

Page End

28

Print ISSN

2090-0783

Online ISSN

2090-0856

Article File

EAJBSE_Volume 10_Issue 1_Pages 21-28.pdf

PDF . 938.1kB

Link

https://eajbse.journals.ekb.eg/article_14457.html

Detail API

https://eajbse.journals.ekb.eg/service?article_code=14457

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3

Type

Original Article

Type Code

687

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, E. Medical Entomology & Parasitology

Publication Link

https://eajbse.journals.ekb.eg/

MainTitle

Does Leishmania infantum Use Degenerating Midgut Cells of The Vector as A Nutrient Source?

Details

Type

Article

Created At

22 Jan 2023