The effects of the aqueous extract of Acacia nilotica and Cuminum cyminum for the control of the brown garden snail "Eobania vermiculata" and the clover land snail "Monacha obstructa" were studied under laboratory conditions. The highest mortality rates were recorded at 25% concentration of Acacia nilotica for both species, 23% and 20% of Cuminum cyminum concentration for the two species, respectively. The extract of Acacia nilotica caused the appearance of black material on the snail shell. The treated snails showed histological alterations in the digestive and salivary glands. The digestive cells were shrunken or completely degenerated. The lumen of the digestive tubules increased in width and filled with secretory materials. Mucocytes of the salivary gland showed great destruction.