ABSTRACT Background: In children, wheezing is a common symptom that needs medical consultations, emergency care services, and hospitalization. The middle ear may behave in a "similar manner to the lungs under allergic inflammatory insults" and that the middle ear may be included in the united airways. Objective: To detect the association between the wheezy chest and the presence of otitis media (OM). Methodology: This study included 100 children with a wheezy chest, 54 male and 46 females; all cases were subjected to entire history taking, clinical examination, complete blood count (CBC) and C- reactive protein (CRP) analysis, otoscopic examination, tympanometry, audiometry, additionally auditory brain stem response (ABR) in non-cooperative children.  Results: In the current study, 47 cases (47%) had bronchial asthma, and 53 cases (53%) had pneumonia. Among the studied cases, 43% had OM (61% suffering from bronchial asthma and 26.4% suffering from pneumonia). Among the 43 cases of OM, 39 cases (90.6%) were complicated by conductive hearing loss (CHL), while 4 cases (9.3%) were complicated by sensory neural hearing loss (SNHL). Anemia has a strong correlation with OM. Conclusion: there is an association between wheezy chest, whether caused by bronchial asthma or pneumonia, and OM development.