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Updates in surgical treatment of vitiligo

Article

Last updated: 03 Jan 2025

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Tags

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Abstract

ABSTRACT
Background: Vitiligo is a common cutaneous disorder of depigmentation. Surgical treatment of vitiligo is considered the final resort of repigmentation in lesions failing to respond for various medical and light therapies. The tissue and cellular graft techniques are used for the successful introduction of melanocytes into the vitiligo lesions. Stability of vitiligo is the cornerstone of evaluation before surgery.  Tissue graft includes various techniques of transferring the healthy pigmented skin as a whole without processing to the vitiliginous skin, while the cellular graft involves further processing of these grafts into cellular components which are then applied on the recipient site after dermabrasion either as such or after multiplication in culture media. Aim: To outline current modalities for surgical treatment of vitiligo. Conclusion: Preparation of recipient-site is considered a crucial step for achieving a successful repigmentation. Multiple promising surgical modalities for vitiligo are continuous in the ongoing research and clinical trials to improve the repigmentation outcomes cosmetically with decreasing the time and the cost.

DOI

10.21608/jram.2020.44431.1086

Keywords

Vitiligo surgery, tissue graft, cellular graft, non-cultured epidermal cells suspension transplantation (NCES), non-cultured outer root sheath hair follicle cell suspension transplantation (NCORSHFS)

Authors

First Name

Alzahraa

Last Name

Gamal

MiddleName

M.

Affiliation

Dermatology and Venereology Department, Faculty of Medicine for Girls, Cairo, Al-Azhar University, Egypt.

Email

alzahraamg13@gmail.com

City

Cairo

Orcid

-

First Name

Rasha

Last Name

El-Barbary

MiddleName

A.

Affiliation

Dermatology and Venereology Department, Faculty of Medicine for Girls, Cairo, Al-Azhar University, Egypt.

Email

dr_rashaderma@yahoo.com

City

Cairo

Orcid

-

First Name

Nayera

Last Name

Moftah

MiddleName

H.

Affiliation

Dermatology and Venereology Department, Faculty of Medicine for Girls, Cairo, Al-Azhar University, Egypt.

Email

nayeramoftah@hotmail.com

City

Cairo

Orcid

0000-0002-2554-8588

Volume

2

Article Issue

1

Related Issue

22700

Issue Date

2021-01-01

Receive Date

2020-10-04

Publish Date

2021-01-01

Page Start

118

Page End

127

Print ISSN

2636-252X

Online ISSN

2636-2538

Link

https://jram.journals.ekb.eg/article_122206.html

Detail API

https://jram.journals.ekb.eg/service?article_code=122206

Order

15

Type

Review Article

Type Code

717

Publication Type

Journal

Publication Title

Journal of Recent Advances in Medicine

Publication Link

https://jram.journals.ekb.eg/

MainTitle

Updates in surgical treatment of vitiligo

Details

Type

Article

Created At

22 Jan 2023