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156796

Antioxidant and Antibacterial Activities of Rosmarinus officinalis aqueous extract with Study of The Pharmaco-Toxicological Effect

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Last updated: 03 Jan 2025

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Abstract

The objective of the present work was to study the antioxidant activity of the aqueous extract and the antibacterial activity of the Rosmarinus officinalis aerial part essential oils. The  Rosemary essential oil yield was equal to 1.47%. A great inhibitory power of Rosemary extract was revealed by the test of antioxidant activity (93.72%) by an IC50 of 16.95 µg/ml, which was superior to that of Butylated hydroxy anisol (BHA a synthetic antioxidant) (6.01µg/ml), and of ascorbic acid (1.27µg/ml).  The essential oil antibacterial activity was evaluated against five bacterial strains, using the aromatogram method. Hence, a remarkable antibacterial activity was noted for Rosemary essential oil.  Gram-positive bacteria were highly sensitive to the activity of this essential oil than the Gram-negative bacteria. Furthermore, pharmacological investigation of the plant aqueous extract revealed the plant had very important pharmaceutical effects (anti-inflammatory effect). The preliminary study of toxicity, according to oral voice, revealed that the Rosmarinus officinalis leaves were not toxic.

DOI

10.21608/eajbsc.2021.156796

Keywords

Rosmarinus officinalis, Antioxidant activity, Antibacterial activity, anti-inflammatory effect, toxicity

Authors

First Name

Rahmani,

Last Name

S.

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Affiliation

Biotechnology and Agronomic Sciences Department, Faculty of Natural Sciences and Life, Hassiba Ben Bouali University of Chlef, Algeria

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Orcid

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First Name

Kanoun,

Last Name

K.

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Affiliation

Laboratory of Molecular Microbiology Health and Proteomics, Biology Department, Faculty of Natural Sciences and Life, Djillali Liabes University of Sidi-Bel-Abbes, BP No. 89 Sidi-Bel-Abbes 22000 Algeria.

Email

khedoudja.kanoun@univ-sba.dz

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Orcid

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First Name

Harir,

Last Name

N.

MiddleName

-

Affiliation

Laboratory of Molecular Microbiology Health and Proteomics, Biology Department, Faculty of Natural Sciences and Life, Djillali Liabes University of Sidi-Bel-Abbes, BP No. 89 Sidi-Bel-Abbes 22000 Algeria.

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Volume

13

Article Issue

1

Related Issue

20278

Issue Date

2021-06-01

Receive Date

2021-01-24

Publish Date

2021-03-15

Page Start

61

Page End

70

Print ISSN

2090-0767

Online ISSN

2090-083X

Link

https://eajbsc.journals.ekb.eg/article_156796.html

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https://eajbsc.journals.ekb.eg/service?article_code=156796

Order

5

Type

Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

MainTitle

Antioxidant and Antibacterial Activities of Rosmarinus officinalis aqueous extract with Study of The Pharmaco-Toxicological Effect

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Article

Created At

22 Jan 2023