The current work was conducted to check the biological effects of the henna tree, Lawsonia inermis ethanol extracts on the Schistocerca gregaria main body metabolites in fat bodies and hemolymph. LC₅₀ of ethanol (8.5%) were applied on penultimate instar nymphs and the metabolite was determined for last instar nymphs and newly emerged adult females. Clearly decreased protein content was determined in fat bodies of late-aged nymphs, after treatment with ethanol extract, as well as of newly emerged adult females. With regard to protein content in hemolymph, strong inducing effects were exhibited on early, mid-aged nymphs and newly emerged adults while reducing effects were exhibited on early-aged nymphs. A reducing effect of L. inermis on the carbohydrate content was observed in fat bodies of late-aged nymphs and newly emerged adults whereas aninducing effect on the nymphs of early ages was displayed. Carbohydrate content in heamolymph has the same trend. A prevalent inhibitory action of L. inermis extracts on the lipid content in fat bodies of nymphs and adults was recorded with few exceptions to mid-aged nymphs. In hemolymph, a major reducing action was achieved on both nymphs and adults, except mid-aged nymphs.