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16302

Physiological effects of envenomation by two different doses of the viper Echis coloratusis crude venom on biochemical parameters in serum of Guinea pigs at different times.

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Last updated: 03 Jan 2025

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Abstract

The eastern carpet viper Echis
coloratusis widely distributed from Africa (eastern Egypt). In the present study the effects of crude venom of the viper
Echis coloratusis on serum biochemical
parameters of guinea pigs. Adult
male guineapigs
(550 ± 25 g body weigh) were divided into three groups (15 each). In the
control group, guinea pigs were interaperitoneally (i.p) injected with 50 µL
saline solution. The second group was i.p.injected
with 0.1µgm/g b.w. of crude venom
in 50 µL saline solutions. The third group was i.p.injected
with 0.2 µgm/g. b.w. of the crude
venom in 50 µL saline solution. The results indicated that the injection of
crude venom of the viper Echis
coloratusis induced a significant decrease in total serum protein,
albumin, globulin and uric acid within
1, 2 and 4 hrs. after injection. In contrast, the
levels of glucose, cholesterol, triglycerides, urea and creatinine were increased
significantly in envenomated Guinea pigs. Viper Echis
coloratusis crude venom caused
hepatic and renal dysfunction in envenomated Guinea pigs.

DOI

10.21608/eajbsc.2009.16302

Keywords

Snake venom, Viper Echis coloratusis, biochemical parameters and Guinea pigs

Authors

First Name

Muhammad

Last Name

Salman

MiddleName

M. A.

Affiliation

Zoology Department, Faculty of Science, South Valley Univesity, Qena, Egypt

Email

salman2_52014@yahoo.com

City

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Orcid

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Volume

1

Article Issue

1

Related Issue

3481

Issue Date

2009-12-01

Receive Date

2018-10-11

Publish Date

2009-12-01

Page Start

21

Page End

31

Print ISSN

2090-0767

Online ISSN

2090-083X

Article File

EAJBSC_Volume 1_Issue 1_Pages 21-31.pdf

PDF . 181.8kB

Link

https://eajbsc.journals.ekb.eg/article_16302.html

Detail API

https://eajbsc.journals.ekb.eg/service?article_code=16302

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2

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Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

MainTitle

Physiological effects of envenomation by two different doses of the viper Echis coloratusis crude venom on biochemical parameters in serum of Guinea pigs at different times.

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Article

Created At

22 Jan 2023