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16122

Levels of five biochemical parameters in asthmatic patient’s blood as markers for bronchial asthma induced by the house-dust mite allergy

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Last updated: 22 Jan 2023

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Abstract

The study examines the validity of five biochemical parameters as indicators for the activity and intensity of asthma induced by the house-dust mite allergy. Blood samples of forty children (28 males and 12 females of 0.5 - 15 years old) suffering from moderate (31) and severe (9) attack of asthma and of 10 non asthmatic children (6 males and 4 females of similar age range) were examined. Levels of histamine, total serum IgE, SIgE, ECP and AEC were significantly higher in the asthmatic- than in the normal cases. Furthermore, severe asthmatic cases had significantly higher levels as compared to the moderate ones, i.e., mean values for [Moderate < Severe] > Check cases. As a conclusion, the elevated levels of such biochemical parameters are associated with HDM asthmatics and are correlated with the severity of asthma attacks. Thus these five parameters may be considered as good markers for HDM asthma activity and severity.

DOI

10.21608/eajbsc.2012.16122

Keywords

HDM allergy, histamine, Immunoglobulin E, Eosinophil cationic protein, Absolute eosinophil count, Asthmatic patients. Cairo, Egypt

Authors

First Name

Yousry

Last Name

El-Zohery

MiddleName

Z. A.

Affiliation

Department of Hematology and Immunology, Faculty of Medicine, Al-Azhar University

Email

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City

-

Orcid

-

First Name

Mohamed

Last Name

Kenawy

MiddleName

A.

Affiliation

Department of Entomology, Faculty of Science, Ain Shams University, Cairo

Email

mohamedkenawy85@yahoo.com

City

-

Orcid

-

First Name

Ashraf

Last Name

Awad

MiddleName

A.

Affiliation

Department of Entomology, Faculty of Science, Ain Shams University, Cairo

Email

-

City

-

Orcid

-

First Name

Nadia

Last Name

Helmi

MiddleName

-

Affiliation

Department of Entomology, Faculty of Science, Ain Shams University, Cairo

Email

-

City

-

Orcid

-

First Name

Akila

Last Name

El-Shafei

MiddleName

M.

Affiliation

Department of Entomology, Faculty of Science, Ain Shams University, Cairo

Email

-

City

-

Orcid

-

First Name

Yousrya

Last Name

Abdel-Hamid

MiddleName

M.

Affiliation

Research Institute of Medical Entomology, The General Organization for Institutes and Teaching Hospitals, Ministry of Health, Dokki, Giza, A.R. Egypt.

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-

City

-

Orcid

-

Volume

4

Article Issue

1

Related Issue

3464

Issue Date

2012-12-01

Receive Date

2018-10-08

Publish Date

2012-12-01

Page Start

25

Page End

30

Print ISSN

2090-0767

Online ISSN

2090-083X

Article File

EAJBSC_Volume 4_Issue 1_Pages 25-30.pdf

PDF . 169.9kB

Link

https://eajbsc.journals.ekb.eg/article_16122.html

Detail API

https://eajbsc.journals.ekb.eg/service?article_code=16122

Order

4

Type

Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

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Article

Created At

22 Jan 2023