Anemia is a global public health problem affecting both developing and developed countries with major consequences for human health as well as social and economic development. The aim of this study to assess the role of information sources in anemia awareness. This cross-sectional community-based study was conducted throughout the Qassim region which has been divided into 11 provinces were evaluated. A total of 1281Saudi citizens participated in this study. Each participant was asked to answer a total of 18 questions from a pre-piloted questionnaire. 1281 questionnaires were distributed the response rate was 95.7%. Males represented 62.2%. General knowledge of anemia was 89.5% of the study population. Satisfactory, fair, and poor awareness of anemia represented 20.5%, 50.5%, and 29.0% respectively. Friends and relatives were constituted the major information sources while books and journals were the lowest source. We conclude that general awareness of anemia is very good, but still more efforts should be performed through information sources to boost of anemia awareness in Saudi population in Qassim area to reach satisfactory knowledge, which reflect in life style and hygiene behavior.