The present study was designed to finding the influence of renal dialysis in some haematological, electrolytes and biochemical parameters in kidney failure and kidney failure with hepatitis patients (C and B) virus. The experiment was designed from ten normal healthy patients as control group and sixty male human patients were selected from hospital campus of the ZagazigUniversity conducting adialysis three time aweek and classified according to dialysis into two major groups, the first group: patients with less than one year of dialysis. The second group: patients with more than one year of dialysis. Each group are divided into three sub groups are renal failure, renal failure with hepatitis c virus (HCV) and renal failure with hepatitis B virus (HB), asignificant decrease was recorded in RBCs count, Hb, HCt and platelets count, also asignificant decrease was showed in serum sodium and calcium levels, while asignificant increase was demonstrated in WBCs count, serum potassium, phosphorus levels and transaminases (ASAT and ALAT) enzymes activities in patients with renal failure and renal failure with hepatitis (C and B) virus .