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16037

Assessment of Oral Cellular proliferative activity among Toombak Dipper in Al-Obeyed City, Sudan

Article

Last updated: 03 Jan 2025

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Abstract

Background: Many factors have been identified as important causative agents that responsible for the development of oral precancerous and cancerous lesions. In Sudan, Toombak have been identified as a major risk factor. Therefore, the aim of this study was to assess the cellular proliferative activity that associated with Toombak use. Methodology: In this study 75 apparently healthy individuals were selected for this study, of whom 50 were currently Toombak users (cases) and 25 were non-Toombak users (controls), Pap. Method and Silver technique were used for the staining of oral smears. Results: Cytological atypia was identified in 10 cases and 4 controls. The mean count NORs count was 4.6 in cases and 2.2 in controls. Conclusion: Toombak is a major risk for occurrence of cellular proliferative activity features that may progress in to oral precancerous or cancerous lesions.

DOI

10.21608/eajbsc.2014.16037

Keywords

Toombak, Cytological atypia, oral cancer, Al-Obeyed

Authors

First Name

Awad

Last Name

Alobaid

MiddleName

Eljeed Abugooda

Affiliation

Department of Histopathology and Cytology, Medical Laboratory Sciences, Al-yarmouk College, Khartoum, Sudan.

Email

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City

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Orcid

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First Name

Ibrahim

Last Name

Elemam

MiddleName

Bakhit Yousef

Affiliation

Department of Histopathology and Cytology, Medical Laboratory Sciences, Al-yarmouk College, Khartoum, Sudan.

Email

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City

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Orcid

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First Name

Mohammed

Last Name

Alsheikh

MiddleName

Abed Algader

Affiliation

Department of Histopathology and Cytology, Medical Laboratory Sciences, Al-yarmouk College, Khartoum, Sudan

Email

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City

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Orcid

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First Name

Abdalhafeez

Last Name

Mahmud

MiddleName

Osman

Affiliation

Department of Pathology, College of Medicine, University of Hail, KSA

Email

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City

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Orcid

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First Name

Hussain

Last Name

Ahmed

MiddleName

Gadelkarim

Affiliation

Department of Pathology, College of Medicine, University of Hail, KSA

Email

he.ahmed@uoh.edu.sa

City

-

Orcid

-

Volume

6

Article Issue

2

Related Issue

2654

Issue Date

2014-12-01

Receive Date

2018-10-06

Publish Date

2014-12-01

Page Start

107

Page End

113

Print ISSN

2090-0767

Online ISSN

2090-083X

Link

https://eajbsc.journals.ekb.eg/article_16037.html

Detail API

https://eajbsc.journals.ekb.eg/service?article_code=16037

Order

13

Type

Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

MainTitle

Assessment of Oral Cellular proliferative activity among Toombak Dipper in Al-Obeyed City, Sudan

Details

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Article

Created At

22 Jan 2023