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251817

Extraction and Identification of Bioactive Compounds from Archachatina marginata (Giant African Land Snail).

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Last updated: 22 Jan 2023

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Abstract

Molluscs are important natural sources of many biologically active compounds. Giant snails (Achatina maginata) have been used in folklore medicine to treat liver diseases, anaemia, and constipation among other medicinal uses.  The aim of this research is to extract and identify bioactive compounds present in Archachatina marginata. Ten giant African land snails were collected from a snail farm during the dry season at Badore, Ajah, Lagos. 20g of fresh tissue of the snails was used for extraction with methanol. Methanolic extraction using Chellaram, Gas Chromatography and Mass Spectrometer (GC-MS), and Fourier Transform Infra-Red Spectroscopy (FT-IR) was conducted in the identification of the bioactive compounds. The FT-IR analysis provided seven peaks for the two samples, and the spectra of both samples were discovered to be in wavenumber range between 4000-600 cm-1 with a resolution of 4cm-1. The GC-MS in comparison of the mass spectra of the constituents, with the National Institute of Standard and Techniques (NIST14), identified twenty chemical constituents including carotenoids, esters, fatty acid, phenols, and Oleanolic Acid-amino Acids Derivatives and phthalates were characterized.  The methanol-based extracts exhibited significant bioactive constituent levels, and their anti-oxidant characteristics find great application in traditional medicine and pharmaceutical industries. They act as antioxidants which play important roles in inhibiting and scavenging free radicals, thus providing protection to humans against infections and degenerative diseases. Conclusively, twenty bioactive compounds were extracted and identified in Achantina marginata. The novel compounds obtained from A. marginata will be of high potential for antioxidant activity.

DOI

10.21608/eajbsz.2022.251817

Keywords

Achantina marginata, bioactive compounds, Carotenoids, esters, fatty acids, phenols, and amino Derivatives

Authors

First Name

Ovioma,

Last Name

O.

MiddleName

G.

Affiliation

Department of Biological Sciences, School of Science,Yaba College of Technology, Yaba Lagos.

Email

godwin.ovioma@yabatech.edu.ng

City

-

Orcid

-

First Name

Ojokuku,

Last Name

A.

MiddleName

S.

Affiliation

Department Chemical Science, College of Technology, Lagos.

Email

-

City

-

Orcid

-

First Name

Kuteyi,

Last Name

R.

MiddleName

T.

Affiliation

Department of Chemical Science,Yaba College of Technology, Yaba Lagos.

Email

-

City

-

Orcid

-

First Name

Saanu,

Last Name

I.

MiddleName

A.

Affiliation

Analytical Chemist, Yaba College of Technology Central Laboratory.

Email

-

City

-

Orcid

-

First Name

Olusegun-Joseph,

Last Name

S.

MiddleName

T.

Affiliation

Department of Science Laboratory Technology, Yaba College of Technology, Lagos

Email

-

City

-

Orcid

-

First Name

Apena,

Last Name

O.

MiddleName

L.

Affiliation

Department of Biological Sciences, School of Science,Yaba College of Technology, Yaba Lagos.

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-

City

-

Orcid

-

Volume

14

Article Issue

2

Related Issue

35359

Issue Date

2022-12-01

Receive Date

2022-05-27

Publish Date

2022-08-03

Page Start

79

Page End

88

Print ISSN

2090-0759

Online ISSN

2090-0821

Article File

EAJBSZ_Volume 14_Issue 2_Pages 79-88.pdf

PDF . 827.4kB

Link

https://eajbsz.journals.ekb.eg/article_251817.html

Detail API

https://eajbsz.journals.ekb.eg/service?article_code=251817

Order

5

Type

Original Article

Type Code

672

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, B. Zoology

Publication Link

https://eajbsz.journals.ekb.eg/

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Article

Created At

22 Jan 2023