63756

Magnetic Field Improves the Efficiency of Low Dose Cis-Platin by Alteration the Oxidative Stress in Ehrlich Carcinoma-Bearing Mice

Article

Last updated: 03 Jan 2025

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Abstract

50 Hz and 50 mT magnetic field (MF) with an exposure period of 30 min./day for 15 days was used to enhance the efficiency of a low dose of cisplatin on BALB/C mice. Tumor tissues were evaluated by oxidative stress parameters such as superoxide dismutase (SOD) enzyme activity, malondialdehyde (MDA) and glutathione (GSH) levels. The result shows that treatment with MF and cisplatin decreases the activity of SOD and GSH level and increases the MDA level compared to the treatment with MF or cisplatin alone. In conclusion, these results reveal that MF improves the therapeutic efficiency of cisplatin.

DOI

10.21608/eajbsz.2019.63756

Keywords

Cisplatin, MF, Ehrlich carcinoma

Authors

First Name

Monira

Last Name

Rageh

MiddleName

M.

Affiliation

Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt

Email

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City

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Orcid

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First Name

Ebtesam

Last Name

Mohamad

MiddleName

A.

Affiliation

Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt

Email

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Orcid

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First Name

Marwa

Last Name

El-Garhy

MiddleName

R.

Affiliation

Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt

Email

marwaelgarhy123@gmail.com

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Orcid

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Volume

11

Article Issue

3

Related Issue

8588

Issue Date

2019-11-01

Receive Date

2019-10-21

Publish Date

2019-11-01

Page Start

107

Page End

112

Print ISSN

2090-0759

Online ISSN

2090-0821

Link

https://eajbsz.journals.ekb.eg/article_63756.html

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https://eajbsz.journals.ekb.eg/service?article_code=63756

Order

7

Type

Original Article

Type Code

672

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences, B. Zoology

Publication Link

https://eajbsz.journals.ekb.eg/

MainTitle

Magnetic Field Improves the Efficiency of Low Dose Cis-Platin by Alteration the Oxidative Stress in Ehrlich Carcinoma-Bearing Mice

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Article

Created At

22 Jan 2023