Two different localities were selected for the present investigation. Generally, out of 200 Mugil cephalus individuals examined, 63 (31.5%) were found to be infected. Out of 119 M. cephalus, 44 (36.9%) collected from Lake Qarun at Fayoum in Egypt were found infected. On the other hand, out of 81 M. cephalus, 19 (23.45%) collected from Missurata fish market in Libya were found infected. The collected parasites from Egyptian specimens were Trematoda, Acanthocephala, Trichodina and Myxosporea. The incidences of infection were 88.6%, 27.2%, 95.5% and 27.3%, respectively. Parasites of the Egyptian mullets includes: 4 species of trematoda (Haplosplanchnus caudatus, H. pachysomus, Lecithobotrys putrescens and Dicrogaster contractus);one species of Acanthocephala (Neoechinorhynchus sp.); three species of Trichodina (Trichodina lepsii, T. puytoraci and T. batala) and one species of Myxosporedia (Myxobolus sp.). It is worth mentioned that protozoan infections were restricted in Egyptian mullets. On the other hand, out of 81 M. cephalus, 19 (23.45%) collected from Missurata were found infected by two genera of trematodes (Vitellibaculum girelia and Lecithocladium exisum).