Background: Fisheries resources are being depleted due to over-exploitation and inadequate information for planning and management; therefore, data on growth pattern, mortality, and exploitation rates of fisheries resources are essential for effective management and sustainable exploitation. Method: Growth parameters, mortality rates, and longevity of the Guinean tilapia, Tilapia guineensis, (Bleeker, 1852) in Asejire Lake were obtained from length composition data from January, 2013 to December, 2013. Results: The von Bertalanfy growth function estimates were: L∞ = 30.98 cm Total length, K = 0.37 year^-1 and t₀ = -0.441. Total mortality rate (Z)was 1.19 year^-1, natural mortality rate (M) was calculated as 0.92 year^-1 , fishing mortality rate (F) obtained was 0.27 year^-1, and the exploitation rate (E) was 0.23. Growth performance index (ø) computed as 2.55. Conclusion: This result indicates low growth rate. The stock was not overexploited since exploitation rate was less than the optimal exploitation rate(0.5).