76148

CAMEL MILK AND DANDELION LEAVES AQUEOUS EXTRACT AS ADJUVANTS FOR CONTROLLING AGAINST LIVER INJURY

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Last updated: 03 Jan 2025

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Abstract

The liver disease all over the world had a more attention towards the prevention methods; balanced diet can be effective and protective. Therefore, the objective of this study was to investigate the hepatoprotective role for dandelion leaves aqueous extract (prebiotic), camel milk, fermented camel milk (probiotic product), fermented camel milk fortified with dandelion leaves aqueous extract (Synbiotic product), camel casein and camel whey protein against carbon tetrachloride (CCl4) induced liver injury in rats. Rats were divided into eight groups (eight rats each). Group one was served as normal control (NC), while the other seven groups were injected intraperitoneal in beginning of experimental with single dose from carbon tetrachloride (CCl4). Animals from group three to seven received orally camel milk; dandelion leaves aqueous extract; fermented camel milk (probiotic product); Synbiotic product and whey camel milk; while, group eight received basal diets in which protein was replaced with 20% camel casein for 45 days. The results indicated that all previous materials exhibited scavenging activity; liver injury control group revealed increased in liver function (AST, ALT and ALP) and malondialdehyde (MDA) levels; whereas, decreased body weight gain, albumin and glutathione reduced (GSH) levels. Also, histological examination of hepatic showed more alteration due to carbon tetrachloride (CCl4) induced hepatocellular damage. While, treatment by dandelion aqueous extract(prebiotic), camel milk; fermented camel milk (probiotic product); fermented camel milk fortified with dandelion leaves aqueous extract (Synbiotic product), camel casein and camel whey protein resulted in a significant improvement in weight gain, liver function and oxidative stress parameters; also, suppresses the alteration in liver histology. It could be concluded that dandelion leaves aqueous extract (prebiotic), camel milk; fermented camel milk (probiotic product); fermented camel milk fortified with dandelion leaves aqueous extract (Synbiotic product), camel casein and camel whey protein should be used as ingredients in functional foods for hepatoprotective.

DOI

10.21608/ajs.2019.16623.1082

Keywords

camel milk, probiotic, Dandelion, Liver Injury, Rats

Authors

First Name

marwa

Last Name

yousef

MiddleName

-

Affiliation

Dairy Science and Technology, Agriculture, Ain Shams University,Cairo,Egypt

Email

marwanet410@gmail.com

City

-

Orcid

0000-0002-3020-021X

First Name

Mohamed

Last Name

El-Hofi

MiddleName

-

Affiliation

Dairy Science and Technology, Agriculture, Ain Shams University,Cairo, Egypt.

Email

prof.dr.hofi@hotmail.com

City

-

Orcid

-

First Name

Ihab

Last Name

Ashoush

MiddleName

Salah

Affiliation

Food Science and Technology Dept, Faculty of Agriculture, Ain Shams University

Email

ihab.ashoush@gmail.com

City

-

Orcid

0000-0002-0775-7837

First Name

kamal

Last Name

soryal

MiddleName

-

Affiliation

Dairy Production and Technology Unit, Dept. of Animal Breeding, Desert Research Center, Cairo, Egypt

Email

dr.kamalsoryal2019@gmail.com

City

-

Orcid

-

First Name

safaa

Last Name

Abd El-Aziz

MiddleName

-

Affiliation

Medicinal Food, National Organization for Drug Control and Research (NODCAR), Giza, Egypt

Email

safyahmed211@yahoo.com

City

-

Orcid

-

Volume

27

Article Issue

4

Related Issue

11426

Issue Date

2019-11-01

Receive Date

2019-09-08

Publish Date

2019-11-01

Page Start

2,127

Page End

2,137

Print ISSN

1110-2675

Online ISSN

2636-3585

Link

https://ajs.journals.ekb.eg/article_76148.html

Detail API

https://ajs.journals.ekb.eg/service?article_code=76148

Order

7

Type

Original Article

Type Code

668

Publication Type

Journal

Publication Title

Arab Universities Journal of Agricultural Sciences

Publication Link

https://ajs.journals.ekb.eg/

MainTitle

CAMEL MILK AND DANDELION LEAVES AQUEOUS EXTRACT AS ADJUVANTS FOR CONTROLLING AGAINST LIVER INJURY

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Article

Created At

22 Jan 2023