A taxonomic review of the subfamilies Ortaliinae and Sticholotidinae (Coleoptera, Coccinellidae) from Egypt is given at the first time with a description of 7 species. The present investigation deals with two species within genus Rodolia and revealed that genus Rodolia belong to tribe Noviini under the subfamily Ortaliinae in agreement with Nedvӗd and Kovář (1996), while, Alfieri (1976) mentioned this tribe under subfamily Coccinellinae.The taxonomic status of five species within subfamily Sticholotidinae is discussed and revealed that, two species of  Pharoscymnus ovoideus and Ph. Pilosus priesneri, are considered new record in Egypt, according to the recent catalogue whereas,  Alfieri mentioned the two species in his monograph as recorded from Egypt. As mentioned in Alfieri^ʼs monograph Ph. varius not species but a subspecies of species Ph. setulosus, with subspecies of anchorago, bifasciatus, brunneonotatus, and letourneuxi the last three subspecies mentioned as aberrations.  Seven species and subspecies are listed and recorded from Egypt, depending on fresh material collected from the Egyptian fauna and reference insect collections; ALFC, ASUC, CUC, and MAC. The diagnostic characters of subfamilies, tribes, and genera are mentioned and keys to subfamilies, species and subspecies are constructed with illustrations for the identification of species. Geographical distributions in Egypt and world are given.