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15744

Effect of green tea consumption on level of glucose, lipid profile and kidney functions in alloxan induced-diabetic rats

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Last updated: 22 Jan 2023

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Abstract

            In recent years, green tea has become a subject of interest because of its beneficial effects on human health. The purpose of the present study was to investigate the effects of daily oral administration of green tea extract for 6 weeks on plasma glucose, lipid profile and kidney functions in alloxan-induced diabetic rats to show the preventive and curative effects of green tea.             Rats (130-150 g) were divided into 4 groups, normal control rats, diabetic rats, diabetic rats post-treated with green tea and diabetic rats pretreated with green tea. Green tea extract was administered orally for 6 weeks to the third and forth groups (300 mg/kg b.w,). Plasma glucose, triglycerides, HDL and LDL-cholesterol were significantly reduced in post-treated and pre-treated groups while plasma cholesterol was significantly reduced only in post-treated group while plasma creatinine, urea and uric acid levels were significantly reduced in post-treated diabetic   group, but in the pre-treated group creatinine and uric acid levels were reduced, but urea level did not change. It is concluded that the consumption of green tea produced a significant reduction in glucose level in diabetic rats. In addition green tea is capable of improving hyperlipidaemia and the impaired kidney functions in addition to its hyperglycemic control.  

DOI

10.21608/eajbsa.2008.15744

Keywords

green tea, plasma, diabetic rats, lipids, glucose, urea, creatinine, Uric acid

Authors

First Name

Abd-Elraheim

Last Name

Elshater

MiddleName

A.

Affiliation

South Valley University, Faculty of Science, Zoology Department, Qena

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Orcid

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First Name

Muhammad

Last Name

Salman

MiddleName

M. A.

Affiliation

South Valley University, Faculty of Science, Zoology Department, Qena

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City

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Orcid

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First Name

Mahrous

Last Name

Moussa

MiddleName

M. A.

Affiliation

South Valley University, Faculty of Science, Zoology Department, Qena

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Orcid

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Volume

1

Article Issue

2

Related Issue

3405

Issue Date

2008-12-01

Receive Date

2018-10-03

Publish Date

2008-12-01

Page Start

125

Page End

134

Print ISSN

1687-8809

Online ISSN

2090-0813

Link

https://eajbsa.journals.ekb.eg/article_15744.html

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https://eajbsa.journals.ekb.eg/service?article_code=15744

Order

11

Type

Original Article

Type Code

667

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. A, Entomology

Publication Link

https://eajbsa.journals.ekb.eg/

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Article

Created At

22 Jan 2023