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15515

Effect of Ginger Extract Consumption on levels of blood Glucose, Lipid Profile and Kidney Functions in Alloxan Induced-Diabetic Rats.

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Last updated: 03 Jan 2025

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Abstract

In recent years, ginger has become a subject of
interest because of its beneficial effects on human health. The purpose of the
present study was to investigate the effects of daily oral administration of ginger
extract for 6 weeks on plasma glucose, lipid profile and kidney functions in
alloxan-induced diabetic rats to show the ameliorating and partly curative
effects in alloxan induced-diabetic rats (150 mg/kg i.p.(Intrapretonial). Rats (130-150gm)
were divided into 4 groups; normal control rats, diabetic control rats,
diabetic rats post-treated with ginger and diabetic rats pretreated with ginger.
Ginger extract was administered orally for 6 weeks to post-treated and pre-treated
rats, and they were compared with the normal and diabetic groups, respectively.
Plasma glucose was reduced significantly in both post-treated and pre-treated
groups. The post-treatment with ginger extract reduced plasma cholesterol,
triglyceride and LDL-cholesterol, but during the pre-treatment with ginger
extract produced insignificant change only in plasma triglyceride level. The plasma
HDL-cholesterol was significantly increased in post-treated and pre-treated
groups. The plasma creatinine, urea and uric acid levels were significantly reduced
in post-treated group; also in pre-treated group, they were reduced but urea
level statistically did not change. It is concluded that the consumption of ginger
produced a significant hypoglycemic effect in diabetic rats. In addition, ginger
is capable of improving hyperlipidemia and the impaired kidney functions in alloxan-induced
diabetic rats

DOI

10.21608/eajbsa.2009.15515

Keywords

Ginger, Kidney function, glucose, plasma, lipids, alloxan, Rats, diabetic

Authors

First Name

Abd-Elraheem

Last Name

Elshater

MiddleName

A.

Affiliation

South Valley University, Faculty of Science, Zoology Department

Email

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City

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Orcid

-

First Name

Muhammad

Last Name

Salman

MiddleName

M. A.

Affiliation

South Valley University, Faculty of Science, Zoology Department

Email

-

City

-

Orcid

-

First Name

Mahrous

Last Name

Moussa

MiddleName

M. A.

Affiliation

South Valley University, Faculty of Science, Zoology Department

Email

-

City

-

Orcid

-

Volume

2

Article Issue

1

Related Issue

3320

Issue Date

2009-06-01

Receive Date

2018-10-01

Publish Date

2009-06-01

Page Start

153

Page End

162

Print ISSN

1687-8809

Online ISSN

2090-0813

Article File

EAJBSA_Volume 2_Issue 1_Pages 153-162.pdf

PDF . 565.2kB

Link

https://eajbsa.journals.ekb.eg/article_15515.html

Detail API

https://eajbsa.journals.ekb.eg/service?article_code=15515

Order

17

Type

Original Article

Type Code

667

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. A, Entomology

Publication Link

https://eajbsa.journals.ekb.eg/

MainTitle

Effect of Ginger Extract Consumption on levels of blood Glucose, Lipid Profile and Kidney Functions in Alloxan Induced-Diabetic Rats.

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Article

Created At

22 Jan 2023