Hygienic behavior in honey bee (Apis mellifera L.) is measured by determining the rate at which the bee uncap and remove dead sealed broad. This collected review described the mechanism of hygienic against the parasitic mite (Varroa destructor), as well as, the brood diseases (Chalk Brood and American Foulbrood). Breeding hygienic disease resistant bees as an important option was determined by some investigators. However, heritability of hygienic behavior against Varroa was discussed by other investigators. Some researches were conducted to assess the performance of commercially bred honey bee queens sold as resistant to the parasitic mite, V. destructor. Physiological susceptibility and hygienic behavior affect chalk brood disease incidence in worker and drone larvae in honey bees (A. mellifera) took attention by others. Control of American Foulbrood disease in commercial apiaries through the use of queens selected for hygienic behavior was discussed in some articles. A comparison of the hygienic response of Africanized and European (A. mellifera carnica) honey bees to Varroa-infested brood in tropical areas was also investigated. An annotated list contains scope of study, authors and the studied area was concluded.