Background: Road traffic accidents (RTA) make a significant portion of the worldwide burden of disease. About 1.2 million people are killed in road crashes every year, and 50 million are injured, occupying 30 percent to 70 percent of orthopedic beds in developing countries hospitals, and if present trends continue, road traffic injuries are predicted to be the third-leading cause to the global burden of disease, and injury in 2022. Subjects & Methods: One hundred and fifty (150) cases of both sexes and different age groups, with RTA fractures referred to the orthopedic Department at AlHadara University Hospital in Alexandria were included in a cross-sectional observational study in relation to demographic data and the results of relations between demographic data and type of fracture and its site. Results: most cases were males. Pedestrian were common cases in this study, the most common fractures in RTA in this study were femoral fractures followed by tibia. There is a relation between fractured tibia and site of case p value=>0,001, a relation between fractured pelvis, femur and age (p value =, 003 and 0,002) respectively, and a relation between sex and fractured femur p value=0,043. Conclusion AND Recommendations: It is concluded in this study that RTA is a big problem in Egypt especially fractures which managed commonly with operations with high cost on country. Further statistical studies in Egypt concerning road traffic accidents epidemiology causes, type of vehicles, toxicological screening …. Etc. are needed to cover the problem as much as possible to help concerned ministries & agencies to track the problem & thus find solutions to save lives & economy