Background: Drug abuse is one of the most serious threats in several countries; acute toxicity of these drugs was more common in all poison control centers. Objectives: This study aimed to recognize the incidence of acute toxicity of abused drugs Methods: This retrospective study was conducted on 375 patients presented to Poison Control Center (PCC) of Minia university hospital from 1st of January 2017 to 31st of December 2019, data collected regarding socio demographic information, types of toxins, mode of toxicity, clinical manifestations, investigations, and outcome. Results: Patients of this study aged 6 months– 58 years old, hospital stay duration ranged between 1 to 8 days. Combined drugs were the most common type 19.2 %, most patients were males 99.2 %, lived in urban areas 70.1 %, unemployed 91.5 %, single marital status 54.7 %. 41.9 % of patients had intermediate qualification; accidental overdose toxicity is the most common mode of poisoning 69.9 %. Regarding clinical manifestation, most patients had stable vital signs and normal arterial blood gases (ABG), and coma was the commonest manifestation. 91.7 % of patients survived while 8.3 % died. Conclusion: combined drugs addiction is most common between addicts nowadays; also synthetic cannabinoid addiction had increased.
Received in original form: 2 March 2022 Accepted in a final form: 1 July 2022