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213306

Evaluation of Various Scoring Systems in Prediction of Acute Carbon Monoxide Poisoning Outcome

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Last updated: 22 Jan 2023

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Abstract

Background: Carbon monoxide (CO) poisoning is one of the most common fatal poisoning worldwide. Laboratory parameters and imaging studies have been used to predict late cardiac and neurological complications in CO poisoned patients. However, very few studies have applied scoring systems as predictors of CO poisoning outcome. Objectives: To evaluate various scoring systems used in emergency settings [Rapid Emergency Medicine Score (REMS), Modified Early Warning Score (MEWS) and Simple Clinical Score (SCS)] for outcome prediction in acute CO poisoned patients. Methodology: It was a cross-sectional study that was conducted on forty five acute CO poisoned patients. It was composed of two parts; retrospective (From 1 st of January 2020 to 28th of February 2021) and prospective part (From 1st of March 2021 to 30th of June 2021). Patients with major medical conditions, pregnant females, smokers and those exposed to associated trauma and other substances in addition to CO were excluded. Using patients' data on admission, REMS, MEWS and SCS were calculated and compared for prediction of outcome. Results: On admission REMS, MEWS and SCS showed significant elevation in both mechanically ventilated and non-survivors when compared to nonmechanically ventilated patients and survivors. MEWS was excellent predictor for requirement of mechanical ventilation (AUC > 0.9). For mortality prediction; REMS, MEWS and SCS were all excellent (AUC = 1). Conclusion: REMS, MEWS and SCS are simple, rapid, reliable and applicable scoring system in predicting mechanical ventilation requirement and in-hospital mortality in acute CO poisoning.
Received in original form: 31 August 2021 Accepted in a final form: 13 october 2021

DOI

10.21608/ajfm.2022.213306

Keywords

Carbon monoxide (CO) poisoning, REMS score, MEWS and SCS scores, Mechanical Ventilation, mortality

Authors

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Elhawary

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AE

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Affiliation

Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Tanta University, Tanta, Egypt.

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First Name

Sagah

Last Name

GA

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Affiliation

Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Tanta University, Tanta, Egypt.

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Volume

38

Article Issue

1

Related Issue

29570

Issue Date

2022-01-01

Receive Date

2022-01-09

Publish Date

2022-01-01

Page Start

79

Page End

86

Print ISSN

1687-1030

Online ISSN

2636-3356

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https://ajfm.journals.ekb.eg/article_213306.html

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https://ajfm.journals.ekb.eg/service?article_code=213306

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8

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Original Article

Type Code

665

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Journal

Publication Title

Ain Shams Journal of Forensic Medicine and Clinical Toxicology

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https://ajfm.journals.ekb.eg/

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Article

Created At

22 Jan 2023