Alkanna orientalis is a medicinal plant with great importance as traditional medicine. Its distribution and population are considered significance for conservation of such plant to obtain the greatest benefit for the present generation and maintaining the potential for future. Many factors are playing a role in conserving the plant in a good condition; climate change is one among these factors. Therefore, our study is focusing on the impact of climate change on the distribution of Alkanna orientalis in the main growing area in Saint Catherine, Egypt. To address the influence of climate change and have a better understanding of the stress that can affect or cause extension of Alkanna plant from its main habitats, studying the actual state of plant community and its distribution along last decade will give a predicting thought for its behaviour and distribution pattern. Develop a promising strategy for dynamic conservation of Alkanna plant will be discussed.