Panicum turgidum and Phalaris minor are invasive weeds of crop fields in Egypt. The main objective of the present study was to indicate the potentials for utilization of Ruta graveolens shoot aqueous extract and leachate at different concentrations (2.5%, 5.0%, 7.5% and 10.0%) to suppress the germination and growth of P. turgidum and P. minor in Petri dish experiment. Results indicated that the degree of inhibition on seed germination and growth of both the recipient species was largely dependent on the concentration of R. graveolens shoot aqueous extract and leachate. The allelopathic effect was statistically significant at p ≤ 0.05 for most treatments. The results also showed that the plumule length of P. turgidum was more sensitive than that of P. minor and responds more strongly to the increase of concentration of R. graveolens shoot aqueous extract and leachate. On the contrary, radicle length of P. minor was the more sensitive to R. graveolens shoot aqueous extract and leachate. Therefore, R. graveolens extract and leachate may be offer promises for their usefulness as a tool for weed management.