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17891

Synthesis and Reactions of Some Thiazole Derivatives

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Last updated: 03 Jan 2025

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Abstract

A series of novel 2-aminothiazole derivatives (3a-e) has been synthesized by the reaction of 4-[4-
methoxy-3-methylphenyl]-4-oxobutenoic acid (1) with thiourea derivatives (2a-e). The thiazolopyridazine
derivatives (4a-c) and (5) were obtained from the reaction of 4-hydroxy-1,3-thiazole (3a-e) with
hydrazine and phenylhydrazine, respectively. The behavior of the 4-hydroxy-1,3-thiazole (3a-e) toward
acetic anhydride and bromine was also studied. The proposed structures of the products were based on
microanalytical and spectroscopic data.

DOI

10.12816/0010669

Keywords

β-Aroylacrylic Acid, thiazole, Thiazolopyridazine, thiourea

Authors

First Name

Sahar

Last Name

El-Sakka

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Suez University, Suez, Egypt

Email

saharelsakka@hotmail.com

City

-

Orcid

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First Name

Mohamed

Last Name

Soliman

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Suez University, Suez, Egypt

Email

-

City

-

Orcid

-

First Name

Rokaia

Last Name

Abdullah

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Suez University, Suez, Egypt

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-

City

-

Orcid

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Volume

8

Article Issue

1

Related Issue

3748

Issue Date

2013-10-01

Receive Date

2018-10-30

Publish Date

2013-10-01

Page Start

1

Page End

4

Print ISSN

1687-5052

Online ISSN

2090-2786

Article File

CAT_Volume 8_Issue 1_Pages 1-4.pdf

PDF . 55.8kB

Link

https://cat.journals.ekb.eg/article_17891.html

Detail API

https://cat.journals.ekb.eg/service?article_code=17891

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Original Article

Type Code

644

Publication Type

Journal

Publication Title

Catrina: The International Journal of Environmental Sciences

Publication Link

https://cat.journals.ekb.eg/

MainTitle

Synthesis and Reactions of Some Thiazole Derivatives

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Type

Article

Created At

22 Jan 2023