Background: Music is known to have positive effects on humans, enhances learning and aids the healing process. Aim: determine the effects of background Alfa brain music on students' cognition and learning style. Design: A quasi experimental research design was used to conduct this study. Setting; this study was carried out at Nursing Education Department, Faculty of Nursing- Alexandria University.  Subject: The subject of this study comprised of 160 nursing students who were registered in “Scientific Thinking course" during the first semester of the academic year (2021-2022). The subjects were assigned randomly into two equal groups; study and control, 80 students for each. Tools: two tools were used for data collection; Tool I: Visual, Aural, Reading/Writing and Kinesthetic (VARK) inventory, Tool II: Alert Scale of Cognitive Style. Results: It was observed that  there were statistically significant differences between study and control groups and within the study group in the favor of study group after the application  regarding VARK and brain hemispheres as p=0.001. Conclusion: Alfa brain music had positive impact on students' learning as it improves the usage of both brain hemisphere and engaging students with different learning styles. Recommendation: it can be recommended that teacher should use Alfa music during lectures and sections with different specialties and try to use other types of music with its specified purpose.