Background: End Stage Renal Disease (ESRD) is the last stage (5th stage) of CKD. ESRD
is irreversible loss of kidney function and associated with severe morbidity, mortality, high cost for
management and different impacts on general health and patient quality of life. Aim: This study
aimed to assess quality of life (physical, psychological, social and spiritual domains) for patients
with ESRD on HD. Design: Descriptive exploratory design was utilized in carrying out this study.
Setting: The study was conducted in in hemodialysis unit at Urology and Nephrology center
affiliated to Mansoura University. Subjects: A Purposive sample of (60) who are diagnosed with
ESRD, on HD and met the inclusion criteria. Tools: I- Patients interviewing questionnaire II-
quality of life scale. Results: 45% of the studied patients were at age group between 20-<40 years
old and 55% of them were males. There were highly statistically significant positive correlations
between physical dimension scale with psychological dimension scale and social dimension scale of
the studied patients. Conclusion: more than half of the patients had average physical QOL, three
quarters of them had average psychological and social QOL, and all patients had good spiritual
QOL. Recommendation: Further research studies are needed to focus on studying factors affecting
QOL for patients with ESRD on long HD program and replication of the study on other areas for
more generalization.