Aging is an inevitable part of life and the largest risk factor for cardiovascular disease (CVD). Aim: Assess the effect of health promotion nursing intervention on the functional status among elderly with cardiovascular diseases. Design: A Quasi-experimental design was used. Settings: The study conducted in cardiac out patients' clinics and inpatients wards at Al-Orman hospital in Assiut university hospitals. Sample: A random sample of 70 elderly with CVD was divided equally into two groups (35 study and 35 control). The data collection lasted 7 months from the beginning of December 2020 and ending in late June 2021. Tools: Four tools were utilized. Tool I: Structured interview questionnaire, Tool II: Comprehensive Heart Disease Knowledge Questionnaire, Tool III: Instrumental Activities of Daily Living Scale (IADL), Tool IV: Katz Index for Activities of Daily Living. Results: It was noted that 80.0% of the study group achieved full functional level in posttest. Additionally; a statistically significant difference between study group function level and their knowledge level at P<0.001. There was positive correlation between ADL, IADL and cardiac diagnosis in study group y-0.989. Conclusion: Functional level of elderly patients with cardiovascular diseases was greatly affected by a health promotion nursing intervention. Recommendation: Providing further health promotion nurse intervention for elderly with cardiovascular diseases in all health care facilities.