Children who are critically ill are a diverse group with numerous comorbidities. Children's data on
early mobilization interventions is scarce. Moreover, there is inadequate research on mobilization
interventions in the critically ill pediatric patients. The aim of this study was to evaluate the
effectiveness of early mobilization protocol on critically ill children outcomes and their activities of
daily living. The study was carried out at pediatric intensive care unit (PICU) affiliated to Mansoura
University Children's Hospital. Quasi experimental research design was used. A purposive sample
was included 60 children. The total sample was divided into two groups (study and control group);
each group contains 30 children. Data were collected by a structured interview sheet was concerned
with collecting data related to: demographic data, homodynamic parameters, outcomes criteria to
assess the efficacy of early mobilization protocol. Barthal Index Scale to assess activities of daily
living after implementation of early mobilization protocol. In relation to hemodynamic parameters,
there was a statistically significant difference between the study and control groups, all items of
Barthal index score and outcomes criteria. Conclusion: based on the research hypotheses;
homodynamic parameters and daily living activities of critically ill children were better after
implementation of early mobilization protocol. Days of mechanical ventilation and length of stay in
the PICU were shorter. Recommendations: early mobilization should be considered essential in the
overall management of pediatric critically ill patients. Further studies with standardized intervention
protocols and randomized clinical trials are required to evaluate the effectiveness of early
mobilization in this population.