Background: Menopause is a life event that can profoundly affect quality of life among menopausal women. More than 80% of women report physical and psychological symptoms that commonly accompany menopause, with varying degrees of severity and life disruption. Aim of the study to evaluate the effect of educational program on quality of life among menopausal women. The study design: Aquasi experimental study design. Sample: was used purposive sample included 120 menopausal women. The study setting: study was conducted at outpatient clinics of the maternity hospitals affiliated to Ain Shams University hospitals. Tools: Two tools used for data collection, the first tool, an interview questionnaire which divided into four parts. The first for assessing socio demographic characteristics, the second for assessing menstruation history, the third for assessing Women's knowledge about menopausal pre-post\test design to determine the effectiveness of educational program on women's knowledge, the fourth for the assessment women's reported practice toward menopausal symptoms pre-posttest design to determine the effectiveness of educational program on women's practice toward menopausal symptoms. The second tools: menopausal quality of life assessment scale (MENQOL), for assessing menopausal women‘s quality of life by questionnaire. Results: The finding of this study proved the effect of the health educational program on quality of life among menopausal women through; high statistical significant between total score level of menopausal women and total practice score level pre/post educational program, High statistical significant difference between quality of life among menopausal women pre/ post educational program. Conclusion: Health educational program had positive efficient on improving menopausal women‘s knowledge and practice toward menopausal symptoms and improving quality of life among menopausal women. Recommendations: Increase women awareness about peri- menopausal period so reduce the severity of menopausal symptoms. Also further research addressing women's health needs is also essential for improving the quality of life